Smooth Muscle Physiology by Dr Roomi- Ch. 8

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  U N I TII  Textbook of Medical Physiology, 11th Edition GUYTON & HALL   Copyright © 2006 by Elsevier, Inc. Chapter 8: Contraction and Excitation of Smooth Muscle byDr. Mudassar Ali Roomi (MBBS, M. Phil.)  Copyright © 2006 by Elsevier, Inc. CLASSIFICATION OF THE MUSCULAR TISSUE ã Non-striated muscle (smooth muscle) ã Striated muscle (cardiac, skeletal muscle)  Copyright © 2006 by Elsevier, Inc. SMOOTH MUSCLE ã  No cross striations ã Location : in the walls of bloodvessels, hollow viscera ã Function : controls the size of thelumen. ã Shape : each fiber is fusiform inshape. ã Diameter : 3-8 um ã Length : 15-200 um ã  No well developed sarcotubular system. Caveolae are present. ã Nucleus : single, rod- shapednucleus located in the centre of each cell.  Copyright © 2006 by Elsevier, Inc. Cytoplasm of smooth muscle fiber ã E/M shows that actin andmyosin are present in thecytoplasm. ã Actin : diamter is 5-7 nm ã Myosin : diameter 12-16 nm ã actin/myosin ratio : 15/1 ã Desmin intermediate filamentsare also present in thecytoplasm. (dia= 10 nm) ã Dense bodies: intermediatefilaments cross over oneanother to form darkly staining patches.
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