93453603-Pathway-Gout.docx

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FAKTOR GENETIK SEKRESI ASAM URAT BERLEBIHAN THOPI TERAPI FARMAKO (KORTIKOSTEROID) GANGGUAN METABOLISME PURIN TERJADI PADA UJUNG-UJUNG SENDI KAKI PENINGKATAN PERMEABILITAS KAPILER HIPERUREMIA
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   FAKTOR GENETIK SEKRESI ASAM URAT BERLEBIHAN GANGGUAN METABOLISME PURIN HIPERUREMIA HIPERATURASI ASAM URAT PENIMBUNAN KRISTAL MONOATRIUM DI SENDI GOUT KRISTAL ASAM URAT BERSIFAT MENGAKTIFKAN SISTEM KOMPLEMEN KOMPLEMEN C3a , C5a MEMFAGOSITOSI S KRISTAL ASAM URAT PENGELUARAN RADIKAL BEBAS TOKSIK & LEUKOPROTEIN B KEMATIAN NEUTROFIL REAKSI ANTIGEN ANTIBODI PELEPASAN MEDIATOR INFLAMASI PROSTAGLANDIN PENINGKATAN PERMEABILITAS KAPILER PERPINDAHAN CAIRAN & ELEKTROLIT PERPINDAHAN CAIRAN DARI EKSTRAVASKULER & INTRAMUSKULER GANGGUAN TRANSPORTASI ELEKTROLIT GANGGUAN POTENSIAL AKSI KESEMUTAN / FAAL GANGGUAN RASA NYAMAN KELEMAHAN OTOT HAMBATAN MOBILITAS FISIK TERAPI FARMAKO (KORTIKOSTEROID) PENINGKATAN PERMEABILITAS KAPILER SUPRESI SUMSUM TULANG PENURUNAN DAYA TAHAN TUBUH RISIKO INFEKSI THOPI TERJADI PADA UJUNG-UJUNG SENDI KAKI DEFORMITAS PADA KAKI GANGGUAN CITRA TUBUH HAMBATAN MOBILITAS FISIK Kurangnya paparan informasi DEFISIT PENGETAHUAN   MENGELUARKAN ASAM LISOSOM YG BERSIFAT DEKSTRUTIF MERUSAK SERABUT SARAF PERIFER NYERI AKUT NYERI PADA MALAM HARI GANGGUAN POLA TIDUR EDEMA PENEKANAN PADA SARAF PENIPISAN PADA KULIT RISIKO KERUSAKAN INTEGRITAS KULIT   
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